What's your Hotkey/HUD Configuration

It can get in your way while moving, especially if you're starting to use such a configuration. But since the fingers don't need to travel far, it's just a flick of the finger once you get used to it and it's barely noticeable in game if you release a movement key for that short of a time.

Unless you're playing other games where you can't re-define the custom layout and would get confused if you switch from one layout to another, I can recommend to move the entire left hand (provided you're right-handed) one to the right. I use esdf instead of wasd and have more keys around my movement keys available. I consider this very comfortable as I can access ANY of the core weapons reliably and have the additional mouse buttons that my mouse offers free for the most important communication binds (for me: enemy seen, flag seen, attacking, defending, item free).